argyrosis (Argyria) - a disease caused by a lengthy deposition of silver in the human body (and its compounds), or silver dust.Argyrosis characterized by fairly strong irreversible pigmentation of the skin which take a bluish - gray or silver color
argyrosis causes of
In most cases, the disease is caused by prolonged use of silver-containing medicines, as well as after prolonged use of cosmetics,which are based on silver.In addition, there were cases of argyrosis people involved in the processing and production of silver
argyrosis symptoms and for
intensity of pigmentation of the mucous membranes and skin depends on the duration of the ingestion of silver nitrate.When the duration of ten to twelve years, found a very sharp pigmentation of the mucous membranes of the intestines, stomach, mouth, connecting membranes of the eyes and skin.Especially pronounced pigmentation in the open areas of the body.
Small doses of silver compounds are relatively safe, even despite the f
silver particles have a rounded form identically sized brownish grains and predominantly found in the basal membrane during the elastic fibers beneath the epidermis, and in part secreting sweat glands.Less can be observed in the deep dermis, in connective tissue around the sebaceous glands and hair follicles and in the walls of arterioles.
differential diagnosis is carried out with Addison's disease, hemochromatosis and porphyria
Unfortunately today has not yet developed effective treatments for this disease.In order to prevent argyrosis need to take drugs for therapeutic purposes the silver for no longer than four weeks, with the use of oral administration of silver and its salts is still unproven.