Endocrine diseases

Hyperprolactinemia causes and treatment

Hyperprolactinemia causes and treatment

Hyperprolactinemia Hyperprolactinaemia - a disease associated with elevated blood concentrations of prolactin (pituitary hormone).This hormone, along with luteinizing and follicle stimulating hormone, produced in the pituitary gland and controls the work of the endocrine glands (thyroid, ovaries, adrenal glands and testes)


The reasons affecting the increased production of prolactin include:

- The most frequent cause of this condition is an adenoma (tumor) of the pituitary gland.

- Cirrhosis

- Hypothyroidism (decrease in thyroid function)

- Polycystic testicular (ovarian disease)

- Chronic renal failure

- Taking certain drugs (contraceptives, and anti-emetics and anti-depressants)

- diseases of the brain (tumors, encephalitis, meningitis )

Hyperprolactinaemia in most cases occurs between the ages of 20 to 30 years, but there are cases where adolescents, the disease diagnosed at puberty


Elevated levels of prolactin in the b

lood of men and women manifests itself in different ways.

In men: reduced testosterone levels, resulting in decreased interest in sex, develops infertility and impotence.Women: the delay or total absence of menstruation, a violation of ovulation during the menstrual cycle, there is failure of the second phase, the allocation of colostrum or breast milk;due to violations of the menstrual cycle may develop infertility


diagnosis and subsequent treatment of hyperprolactinemia is engaged in endocrinology and gynecology - endocrinologist.The necessary diagnostic procedures include: blood tests to prolactin (and sometimes other hormones), conducting hormone tests;to estimate the size of the pituitary held x-ray of the skull and in particular the "sella";conduct magnetic - resonance and computed tomography;for women - gynecologist consultation;in the case of pituitary adenoma - consultation ophthalmologist


most popular is the therapeutic treatment, in which patients are assigned special drugs (lisuride, parlodel and so forth.), which normalize prolactin levels in the blood, and women restore normal menstrualcycle and fertility.Removal of a pituitary tumor by surgery is used in case of failure of a therapeutic treatment, or in case of disturbances evolved from view.As an additional method of treatment is used radiotherapy.If hyperprolactinemia caused by adrenal insufficiency, or hypothyroidism, is assigned to the treatment of these conditions, resulting in normalized prolactin.One of the methods of treatment of this disease is ionizing radiation, which allows you to locally irradiate the pituitary gland, without affecting the surrounding tissue.

More articles on the topic:

1. Hypoparathyroidism 2. Hyperparathyroidism

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