Infectious diseases

Reiter's disease

disease Reiter

Reiter disease Reiter (Reiter's syndrome) - develops sequentially or simultaneously combined eye disease (conjunctivitis), joints (reactive mono- or oligoarthritis) and urinary organs (usually nonspecific uretroprostatit).Reiter's disease develops with the availability in genetically predisposed people chlamydial infection.Usually the disease develops at a young age, men suffer more than women about twenty times.The peak incidence occurs in the age gap between twenty and forty years of age (80%).There are isolated cases of child morbidity

Reiter's disease - causes of

most often in the development of Reiter's disease in addition to genetic predisposition play a role of various infections of the digestive and urinary systems.Usually the disease begins with urethritis, which occurs after an exacerbation of a chronic urinary tract infection, or after sexual intercourse.In the presence of unfavorable epidemic situation, which is often present in the tourist and military camps, a cata

lyst for the development of Reiter's disease may be acute enterocolitis Yersinia, Salmonella, or shigellosis origin.In the mechanism of joint damage focus is on the family history and immune processes.

Reiter's disease may be caused by certain types of chlamydia, which usually affect the mucous membranes of man getting into his body through the urinary organs and affecting in consequence of other systems and organs.Because chlamydia can be quite long in the body of the patient, high probability of relapse and recurrence of the disease, or development of chronic disease Reiter

Reiter's disease - symptoms

the forefront of the clinical picture of the disease Reier go manifestations of conjunctivitis, arthritisand urethritis.In addition there may be changes in the mucous membranes and parenchymatous organs (CNS, aorta, myocardium, kidney, liver, etc.).

main sequence of symptoms may vary, but most Reiter's disease begins with the development of diseases such as cystitis, urethritis and prostatitis.In this disease urethritis may vary in their severity - from erased prone to prolonged / chronic course, to the island with a strong presence of purulent discharge.Urethritis seen burning, itching, Reiter meager discharge from the vagina and urethra, redness around the opening of the urethra coming and unpleasant sensations when urinating.At discharge usually slimy character.

Soon after a person comes urethritis eye disease that most frequently manifests conjunctivitis, rarely keratitis, optic neuritis, retinitis, uveitis, iridocyclitis, iritis.Conjunctivitis Reiter's disease is most often bilateral, faint and passing after one or two days.Very often it goes unnoticed.

defeat of joints in Reiter's disease is the leading symptom develops after one and a half months after the development of acute urinary infections.The most characteristic lesion is joint damage asymmetric arthritis, is involved in the joints of the lower extremities - interphalangeal, metatarsophalangeal, ankle and knee.Joint pain is usually worse in the morning and at night, the skin over them bloodshot, there is effusion.After a few days there is a consistent characteristic of (upward) joint involvement.Often there is the development of heel spurs, heel bursitis, an inflammation of the Achilles tendon.Some patients have had pain in the spine, which subsequently leads to the development of sarkoileita.

30% of patients the recurrence of arthritis;20% of patients with arthritis becomes chronic wasting adjacent muscles, as well as restriction of joint function;50% of patients with articular symptoms completely disappear.Because of the tarsal joint damage in some patients may develop flat feet.The defeat of the joints of the upper extremities is observed extreme redko.Poryadka 50% of patients exposed to the defeat of the skin and mucous membranes.In the area of ​​the glans penis and the oral mucosa appear painful sores, develop balanitis or balanoposthitis may develop glossitis and stomatitis.The defeat of the skin characterized by the appearance of small size red papules, erythematous spots sometimes.For Reiter's disease is characterized by keratoderma that against the background of the skin redness expressed drain foci of hyperkeratosis with peeling the palms and feet.Also often foci of hyperkeratosis observed on the skin of the trunk and forehead.

syndrome (disease), Reiter's may be a painless swelling of the lymph nodes (usually the groin);at about 20% of patients had signs of heart disease (myocarditis, myocardial), kidney disease (renal amyloidosis, nephritis), nervous system (polyneuritis), the lungs (pleural effusion, focal pneumonia), and long-term low-grade fever body

DiagnosticsReiter's disease

the presence of characteristic triad of this disease (+ urethritis + conjunctivitis, arthritis), diagnosis of Reiter's disease does not cause virtually no difficulties.With the lack of severity of individual symptoms or atypical cases, shown conducting X-ray examination of the joints.Analysis of synovial fluid showed signs of inflammation.Biopsy of synovial fluid will reveal a picture of nonspecific subacute or acute inflammation.Total blood chemistry did not reveal abnormalities.The urine is observed the appearance of pus

Reiter's disease - treatment

Treatment Reiter's disease solely on the destruction of the joints, which is the most disturbing and vivid manifestation of the disease, does not give the desired results, and usually leads to a prolonged or chronic disease.The same result is obtained by treatment with penicillin and cephalosporin groups.It is necessary to treat both the patient and his sexual partner.

Reiter's disease, all medical activities can be divided into the following main areas as anti-inflammatory therapy of articular substance and antibacterial therapy of infection.

Antibiotic treatment of urethritis primarily carried tetracycline drugs.In the treatment of arthritis are used NSAIDs like Voltaren, indomethacin, aspirin, diclofenac, and so on. In the case of high disease activity and pronounced systemic manifestations, shows the use of glucocorticoids.In the case of chronic arthritis or prolonged application shown gold salts or quinoline derivatives.

Primary prevention Reiter's disease is based on the observance of standard sanitary rules, timely treatment of cystitis, urethritis and other urinary infections.In the case of Chlamydia infection, be sure the treatment of both sexual partners.

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