blood cancer (leukemia, leukemia) - a large group of malignant diseases clonal nature of hematopoiesis, which develop due to a mutation of bone marrow cells with subsequent displacement of healthy tissue.Due to the lack of healthy cells of hematopoiesis, the following typical signs of blood cancer: increased susceptibility of the organism to various infectious diseases and bleeding, anemia, cytopenia (reduction of platelets and / or white blood cells).
As with other cancers, the tumor cells of blood cancer can spread to humans, affecting various organs and lymph nodes.The most commonly in late stages of malignancy involving the liver and spleen, but only after other organs.In the case of diagnosis of peripheral vnekostnomozgovoy form of blood cancer metastases initially affect the bone marrow.
Perhaps the main reason for mutation of hematopoietic cells is carcinogenic effects of ionizing radiation, as evidenced by the massive mass detection of blood cancer among residents of th
Cancer Blood - form
common classification of this disease involves the division of the cancer process in two main forms, is an acute and chronic leukemia.For the acute form of blood cancer characterized by the presence of a large number of immature cells that inhibit the normal hematopoiesis.A sign of the chronic form of blood cancer is the prevalence of granular white blood cells or granulocytes, which are gradually replaced by healthy cells.Acute and chronic forms of the disease are positioned as two separate hematological diseases
Blood Cancer - Symptoms
Like most other cancer processes in the initial stages of blood cancer occurs almost asymptomatic.By the early symptoms of malignant disease include the following somatic symptoms: poor zazhivlyaemost wounds, memory impairment (due to poor blood supply to the brain), drowsiness or insomnia, fatigue.The appearance of a patient with blood cancer characterized by increased pallor under the eyes pronounced shadows.Patients constantly suffer from various infections and nosebleeds.Very often there are symptoms of blood cancer as an enlarged spleen, liver, lymph nodes;low-grade fever body.Hematologic signs of blood cancer set, based on the results of laboratory analyzes the patient's blood
Cancer blood - stage
For the initial stage of the acute form of blood cancer characterized by the following symptoms: aggravation of chronic infections, a significant deterioration in general well-being, a slight change of composition of blood (sometimesmay not be available).Advanced stages of blood cancer characterized by pronounced changes in the composition of blood.After the treatment, the developed stage flows into the terminal stage (complete inhibition of the hematopoietic system), or a period of remission.
initial stage of the chronic form of blood cancer characterized by an absolute lack of external symptoms and is often diagnosed by chance in studies of blood due to other diseases.At this stage, blood cancer in the blood there is an increased number of granular leukocytes.To eliminate their excess applies leukophoresis.The second stage of the chronic form of blood cancer manifested form patients with secondary tumors, the occurrence of which is accompanied by a very rapid increase in the number of blast hematopoietic cells, which leads to the overflow of the cancer process in the most difficult stage of the complications in the form of a significant increase in the spleen, liver and generalized lymphadenopathy
Blood Cancer - Diagnostics
If the patient complained about the deterioration of the general state of health, with the enlargement of the spleen, liver and lymph nodes, it is directed to pass deployed and general blood tests.For hematological symptoms of blood cancer include: Blood found in the immature blast cells, and reduced levels of hemoglobin, platelets and white blood cells.
form of blood cancer depends on the type of the selected modified hematopoietic cells.It is set at the last stage of the scan, which is a bone marrow biopsy.To determine the extent of metastatic spread of cancer of the blood is shown holding a CT of the abdomen, head and chest x-ray
Blood cancer - treatment
The prevailing method of treatment of blood cancer is chemotherapy with cytotoxic drugs, lasting about two years (6 months hospital +1.5 year ambulatorytreatment).The initial phase of the treatment of blood cancer is the most difficult period of therapy for the patient, as in the first weeks of the patient is shown holding a continuous intravenous infusion.During the collapse of the tumor blood cancer drug treatment is filling with blood donor red blood cells and platelets.
Throughout the period of hospital treatment must be strictly comply with Sanitary and maximum protect the patient from any contact with the outside world, as a result of the massive destruction of white blood cells in the patient is practically no immune protection.
After the onset of remission period, all further treatment is to consolidate the positive results.In some cases, after several weeks of remission patient with blood cancer shows a course of radiotherapy brain areas.
In the case of recurrence of the disease the patient may be directed to a bone marrow transplant.The best for this procedure a donor can be a relative, and the blood-compatible outsider
blood cancer in children
In children the most common form of blood cancer is acute lymphoblastic leukemia.The disease is approximately 30% of all childhood cancer and 80% of all reported cases of blood cancers in children.The peak incidence of leukemia accounts for the age span from 2 to 5 years.The most at risk of developing cancer of the blood with the presence of children of different chromosomal abnormalities, as well as kids who have been subjected to ionizing radiation in utero or in early childhood.