xanthomas (greasy clam papillomatoznyh fibroids) - is patchy deposition in some tissues and skin cholesterol and triglycerides caused by certain disorders of lipid metabolism.Morphological basis of neoplasms advocate the so-called foam cells, which represent a multi- or mononuclear phagocytes with fat inclusions containing foamy cytoplasm.
There are generalized and local xanthomas.To include local Tuberous (knobby) and xanthoma xanthelasma.
xanthomas disease are not independent - they are a symptom or a result of congenital or acquired disorders of fat metabolism.Large nodular xanthoma often appear in renal disease and diabetes.Crater xanthoma often occur when alcohol abuse, as well as inflammation of the pancreas.
tendon xanthoma developed due to blockage of the bile ducts.In addition, these formations can develop after heavy operations and as a result of various liver diseases.They are also a symptom of diseases such as Lawrence syndrome, syndrome Toytsh
Clinical forms xanthomas
Plane xanthoma (xanthelasma) is slowly growing benign tumor, is a well-circumscribed or slightly wrinkled, slightly elevated or flat yellow plaque, which are often quite symmetrically located on the oral mucosa,on the ears and the skin of the inner corner of the upper eyelid.Evidence is emerging of education usually older women, who suffer from diseases of the liver or lipid metabolism disorders.The value of this type of xanthomas sensed ranges from millimeters to five centimeters or more.Occasionally there may be a generalized form of flat xanthomas.
Multiple eruptive (nodules) xanthomas represent a multiple yellow hemispherical or flat painless nodules the size of a small pea, with the whisk minor erythema.These tumors are usually located quite scattered throughout the skin, but still a bit more often they can be seen on the extensor surfaces of the lower and upper extremities.At the initial stage of their development, patients often feel a little itchy.Often contributes to the formation of eruptive xanthomas receiving contraceptive drugs.
Tuberous (nodosum) xanthoma looks like a smooth dense hemispherical painless education, up to several centimeters diameter, brown, yellow or orange, which is usually localized in the joints and buttocks.
tendon xanthomas - slow-growing dense tumor formation, located in the region of the extensor tendons of the fingers and the Achilles tendon.Most are asymptomatic, but after the trauma and subsequent inflammation are often painful.
Ksantogranulemy - usually located on the upper half of the torso, scalp and face, having a form of small lesions in diameter from - 0.1 to 2 centimeters.Occasionally these lesions are rare, but more often they are multiple.The shape of the hemispherical ksantogranulemy (seldom flat), with yellowish smooth surface and soft consistency.Cases of systemic lesions.Most often, these formations disappear spontaneously.
Disseminated xanthoma - it is quite rare idiopathic histiocytic granulomas of unknown etiology, which manifest multiple elements to an average size of a pea, and then coalescing into dense flat plaques, from red-brown to orange.Typically, this form of xanthomas is grouped in the mucous membranes, in the folds of skin on the flexor surfaces of large joints.
xanthomas differential diagnosis is carried out with histiocytosis X, retikulogistiotsitomami pseudoxanthoma and elastic.
Independently xanthoma can disappear only when its development caused the elimination of metabolic disorders.Besides shows diet strict limitation alcohol and animal fats.Surgically removed only single xanthomas.
Treatment xanthomas usually held hypocholesterolemic drugs lipotropic action (Methionine, clofibrate, lipoic acid, Lipamid, Parmidin) enterosorbents and vitamins of the complex B. In some cases plasmapheresis is shown.
large single xanthoma showing the removal using cryotherapy, electrocautery, or surgically.
self-medicate these entities should not be engaged.In the case of small yellowish nodules, they can not try to pick out or lubricate any ointments, and you need to consult a dermatologist.A doctor on the basis of examination and the possible additional studies will try to establish the true cause of xanthomas and depending on the results obtained appropriate treatment.In the absence of an accurate diagnosis will be assigned to appropriate diet, combined with the reception of drugs and further supervision of the effectiveness of the prescribed treatment.