Hailey - Hailey disease
Hailey-Hailey (aka benign familial pemphigus) - a rare genetic dermatosis.Clinical manifestations of the disease - the flat flabby bubbles formed by erosion at the opening
Most often this disease is localized in areas of high friction (in the armpits, in the scrotum, under the breasts, on the inner thighs andneck) and manifests blisters turning into erosion.As a result of the merger with each other, the erosion transformed into intricately delineated erythematous plaques
aggravates the course of disease factors
The majority of patients with a diagnosis of Hailey-Hailey peak exacerbation occurs in the summer, as the increased body temperature and sweating seriously worsen the disease.Also contribute to relapse mechanical trauma, scalp electrodes during the procedure electrocardiogram, wearing a stiff collar, and women wearing bras with tight oppressive straps
From - the similarity of many of the symptoms, the disease Hailey-Hailey should be
from other dermatoses differentiate Hailey-Hailey allows that in the disease process has not involved the mucous membranes, and affects mostly intertriginous area
Locally appointed :
- Fluorinated corticosteroid ointment
In cases of prolonged treatment :
- prednisolone (20-40mg per day)
In severe cases, treatment is prescribed methotrexate, thalidomide, dapsone, dermabrasion, PUVA - therapy, vitamin E, as well as laser treatmentcarbon dioxide.
With limited lesions that differ persistent current applied skin transplantation.