Crohn's disease - a chronic inflammatory bowel disease in which the pathological process can occur on any portion thereof.When the disease occurs defeat all layers of the intestinal wall.Crohn's disease is considered to be quite rare disease, but very often in order to establish the correct diagnosis, it takes a long time.There are many cases of misdiagnosis and therefore improper purpose ineffective treatment.Sometimes, the correct diagnosis is established only in the course of surgical intervention for complications of the disease.
According to statistics, in men the disease is detected more often than women.The first symptoms usually occur at a fairly young age - 20-40 years.But there are cases of Crohn's disease in children. Content
causative agent of Crohn's disease today is not found, although the infectious theory
main risk factors for the disease: a viral infectious disease, food allergies, mental strain and stress, smoking, and genetic predisposition.
Because Crohn's disease affects any part of the digestive system symptoms of the disease is very multifaceted and depends on where the main focus of inflammation.There are general and local symptoms of the disease, and also have a place of its extra-intestinal manifestations.
Symptoms such as fever, malaise, weight loss, due to the presence of inflammation in the gut (often affects the large intestine), or any other part of the gastrointestinal tract, resulting in an intoxication syndrome.Increased body temperature to high numbers may indicate the development of septic complications.
With the progression of the disease organism is disturbed absorption of essential nutrients and vitamins.This leads to metabolic disorders, weight loss, the formation of cholesterol in the gallbladder stones.
Abdominal pain is usually not very intense, cramping, patients are often concerned about the heaviness and bloating.If it affects the ileum pain is indistinguishable from that of appendicitis.
Disorders chair.Patients in most cases complain of diarrhea (stools more than 6 times a day), but in some cases may be, and constipation.Constant sign of Crohn's disease - blood in the stool.After defecation abdominal pain weakens.
Extraintestinal manifestations of the disease are associated with immune disorders that affect the entire body:
The course of Crohn's disease with long periods of exacerbation and remission.Patients can over the years not to know about his illness until you are her first exacerbation.
main treatment of the disease - medical, surgical intervention is required only in the development of complications.
During remission patients must be observed strict diet, not to provoke aggravation of inflammation in the intestinal wall.Meals patients should be balanced, contain large amounts of protein and vitamins, and fats should be limited.It is necessary to completely eliminate from the diet of coarse fiber plant foods and alcohol that irritate the intestinal wall.All products are also excluded, promote the development of diarrhea and bloating.
During an exacerbation patients assigned antibiotic therapy, duration of the course is more than a month.Taking antibiotics is most effective when the disease affects the large intestine.
There is a group of drugs with anti-inflammatory effects, which are specifically designed for the treatment of Crohn's disease (sulfasalazine, Mesalazine, Pentas).The dosage of the drug is prescribed by a doctor depending on the severity of the disease, the patient's age and stage of disease.
In order to suppress the excessive activity of the immune system of patients received corticosteroids (prednisolone, hydrocortisone).With the same purpose, patients are assigned immunosuppressants (MTX) - drugs that help maintain remission of Crohn's disease.
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