May
17
23:01
Gastroenterology

Treatment of giardiasis in adults

As is known, giardiasis is a parasitic disease caused by a microscopic flagellated protozoan class - Giardia.They often settle in the upper part of the small intestine and occur as active vegetative forms and cysts.

Content

  • 1 As a person becomes infected with Giardia
  • 2 What do giardia in the body
  • 3 Symptoms of giardiasis
    • 3.1 Intestinal
    • 3.2 Hepatobiliary
    • 3.3 asthenoneurotic
    • 3.4 toxic-allergic
  • 4 It is interesting to know
  • 5 Diagnostics
  • 6 treatment of giardiasis in adults
      • 6.0.1 first phase lasts no more than2 weeks and includes the following treatments:
      • 6.0.2 The second stage involves taking drugs that act on the simplest example:
      • 6.0.3 The third stage aims to consolidate the achieved results and includes the following 2-3 weeks:

Usually infection occurs in cases when Giardia cysts ingested with food (such as vegetables, fruits, berries), drinking water, as well as poor hygiene (dirty hands, flies).In
environment Giardia retain their abil

ity to infect a sufficiently long time - in the soil about 3 weeks, and in drinking water of up to 3 months.According to some studies, the cysts are found even in seawater (viability of about 1.5 months) and dairy products (3.5 months).
After Giardia way or another got into the stomach, their fate depends on the general state of the human immune system and the number of cysts caught: the weaker the immune system and the greater the number of cysts, the higher the probability of giardiasis.

ingested cysts fall from the stomach into the small intestine starting where they dissolve the outer shell, and cysts are converted into its active vegetative form.Then they are sent to the brush border of intestinal microvilli, and are beginning to eat that was absorbed microvilli: amino acids, lipids, carbohydrates, minerals and vitamins.The result of the activity
lamblia impaired digestive enzyme formation, reduced flow necessary substances in the blood, including fat-soluble vitamins, as well as ascorbic acid.Gradually destruction of cells of the intestinal mucosa, which is accompanied by inflammation or atrophy.
Once in the host's intestine, Giardia reproduce very quickly, actively populating more and more territory.In the end, on the mucous membrane of the small intestine in Q1.see can simultaneously live over 1 million Giardia, so the whole process of formation of a new division and giardia is only 15-20 minutes.
favorite place of life of the parasite - the small intestine (sometimes involving the duodenum).Then giardia gradually move to more remote parts of the small intestine.The products of their decay and life are absorbed into the bloodstream and cause sensitization (new or worsening symptoms of allergies).
Constant inflammation of the intestinal mucosa due to the activity of giardia leads to such phenomena as dysbiosis, biliary dyskinesia, recurrent abdominal pain or violation of the chair.

Almost half the people know that infected with Giardia, only the results of fecal Giardia cysts.In other words, the patient does not even suspect that he giardiasis.
In other cases, there may be the following forms of the disease:

There is also a mixed form of the disease.

Some experts called giardiasis "parasite anguish and sorrow" because the disease manifests itself in some cases, tearfulness, irritability and depressed mood.
Sometimes giardiasis may be a "multi-colored skin," is characterized by uneven coloring of various parts of the body and a touch of jaundice due to cholestasis.
dry skin and chapped lips - this symptom can also occur in giardiasis, with red border not only quickly become weather-beaten, but it can occur cracks and "perleches."
anemia, palpitations, joint pain, dizziness, not treatable inflammation of the eyelids, irritable bowel syndrome, unexplained fever, and so on. N. Also occasionally occur in giardiasis and disappear only after the end of treatment.

Fecal on I / g.If Giardia cysts were found in the feces, the diagnosis is confirmed.However, it should be remembered that the cysts are not always present - in some cases they may not be in the feces within 20 days, and then appear briefly and disappear again (and so constantly).For this reason, it is best to take the study of feces on 1 day a week for at least 4-5 weeks in a row.
study of duodenal contents.In some cases it is possible to detect active vegetative forms of the parasite.
serological blood tests for antibodies.
Also, when giardiasis can be observed persistent eosinophilia, decrease in hemoglobin.

giardiasis Treatment in adults should be performed only by a physician or a gastroenterologist and infectious diseases by no means alone.It is carried out in 3 stages:

Diet worsening reproduction lamblia (restriction of refined carbohydrates, fiber and plenty of meatless dishes).
Improving outflow of bile (cholagogue grass and preparations: everlasting, corn silk, febihol and so on. N.).
Enterosorbents to relieve symptoms of toxicity (Polyphepan, Enterosgel, Polysorb, activated charcoal).
antiallergic agent (loratadine, Diazolin, Tsetrin, desloratadine).
Enzyme preparations to improve digestion (Mezim forte, pancreatin or Creon).

metronidazole (400 mg three times a day, 5-10 days),
Ornidazole (day or 5-10-day course of the drug),
Fazizhina (treatment 1-2 days, 1 tablet of 0.5 g 4 timesper day),
albendazole (0.4 1 g once a day for 5 days) and m. p.
Also at this stage continues reception antiallergic agents, enzymes and sorbents.
Depending on the drug regimen and duration of antiparasitic therapy may range from a few days to a week or more.In some cases, the standard scheme provides for a repeated course after 1-2 weeks.

Among folk remedies to improve the general well-being and creating unfavorable conditions for the reproduction of the parasite used: Birch juice, carrot and beet juice, tincture of walnuts.