May
13
23:01
Gastroenterology

Chronic pancreatitis: Symptoms and Treatment

Given that the process of pathogen in chronic pancreatitis can last for years, its appearance is not as bright as the symptoms of acute disease of the pancreas.But the consequences can be very sad, because as a result of repeated and progressive inflammation normally functioning breast tissue is replaced by connective.This in turn leads to reduced production of enzymes involved in digestion, important hormones (e.g., insulin) and a number of biologically active substances.Therefore, all patients need time to identify the symptoms and observe prescribed by the doctor timely and adequate treatment.

Content

  • 1 Clinical symptoms
  • 2 pain syndrome
  • 3 Dyspeptic syndrome
  • 4 syndrome lack enzymes
  • 5 intoxication syndrome
  • 6 syndrome hormoneviolations
  • 7 Compartment syndrome
  • 8 Treatment
  • 9 Dietotherapy
  • 10 Pharmacotherapy
  • 11 Physiotherapy
  • 12 Surgery

later discovery of chronic pancreatitis sometimes requiressignificant changes in the daily lives of patients.One has t
o completely change food.Others are forced to constantly take drugs.And the third has to lie down on the operating table.In time to find the "enemy" and start with him a victorious struggle, it is worth recalling its clinical manifestations.After all, they lead us in the doctor's office or in a hospital bed.

Despite the difference in the complaints and expression in different patients with chronic pancreatitis, the symptoms can be grouped into a few characteristic syndromes.They are:
• pain;
• dyspeptic syndrome (a malfunction of the stomach);
• syndrome of lack of enzymes;
• intoxication syndrome;
• syndrome, hormonal disorders;
• compartment syndrome.

Pain is the most specific and frequent manifestation of the disease.As a rule, it is triggered by dietary disorders (fried, fatty, smoked, spicy, hearty food or alcohol) or increases after them.
Chronic pancreatitis: Symptoms and Treatment Its location can vary considerably.Classical localization is considered to be the left upper quadrant.It is typical for inflammation, hit the tail of the pancreas.Such pain often have a distinctive character shingles.If you find a pathological process in the body of head pain occurs in the upper right abdomen.In case of defeat cancer in the body of the patient epigastric pain.In addition, the pain may resemble a renal colic, if they are located in the lower back (its left side).Moreover, some patients are not able to determine the location of a distinct pain.
intensity of pain are also often different.In some patients it is painful and long, while others feel only discomfort, and in certain "lucky" she absent.Unfortunately, not always the absence or disappearance of pain indicates a cure.Painless forms inherent in patients with stones in the pancreatic tissue, diabetes and those with a significant portion of cancer has changed its structure and has ceased to operate normally.

During acute patients are often concerned about the deterioration of appetite, persistent nausea, persistent vomiting, not leading to the relief of bloating.These symptoms occur simultaneously with pain or independently from it.

death of cells synthesizing pancreatic enzymes leads to the fact that not enough food components are split and therefore not absorbed.There are abundant, rapid, sticky and loose stools.In the gray feces visible whole pieces of undigested food.Enhanced bloating.Patients gradually lose weight, they appear different hypovitaminosis, anemia.Some syndrome manifest allergic reactions to food hitherto well-tolerated in the form of rashes, runny nose, shortness of breath.

To this syndrome include fever, malaise, increased heart rate, the occurrence of bleeding.In chronic pancreatitis, it occurs rarely, and indicates an extremely serious situation.

while replacing normal pancreatic tissue to be destroyed and fibrotic cells producing hormones (glucagon, insulin and others.).These clusters are located in the tail of the gland.
the early stages of the pancreas tries to compensate for the loss, so it enhances the formation of hormones.Thus, when forced hyperinsulinism patients concerned about cold sweat, trembling, sudden weakness, hunger, excitement, fear.Then gradually patients experience symptoms associated with a deficiency of these hormones.For example, can manifest symptoms of diabetes mellitus: thirst, excessive urination, and others.

swelling of the head of the pancreas, it may increase substantially and squeeze located near blood vessels, bile duct, duodenum.When the pressure in the splenic vein increases spleen.Signs of compression of the portal vein is an increase in the stomach because of accumulated excess fluid (ascites).In the case of cross-duodenal disorders, patients develop debilitating vomiting.In blocking the biliary tract, patients turn yellow, their exhausting itching.
In the first decade of the disease is dominated by pain, which is often combined with dyspeptic complaints.A further pains disappear or substantially decrease, and the symptoms predominate lack of enzymes and / or hormones.

Writing patient treatment plan forthcoming, the doctor puts a very definite purpose.It should be:

To achieve these goals, the non-surgical treatment options for patients with all chronic pancreatitis should be applied different methodologies.The combined effects of different therapeutic factors (diet therapy, medication, physical therapy, etc..) More effectively.

If exacerbation of chronic pancreatitis seriously enough and is accompanied by severe pain, persistent vomiting, significant changes in laboratory samples, the patients need hunger.It allows for maximum inflammation of the peace and minimize the production of gland aggressive enzymes that destroy the body.Its duration depends on the particular clinical case, but usually is from 1 to 3 days.Sometimes, in the "hungry" phase may be drinking a decoction of rose hips, alkaline mineral water, weak tea.
then appointed a special low-calorie diet (2,200 kcal) protein with the normal quota.It is designed to maximize sparing the pancreas and other digestive organs.The features of this diet are:

Provided clinical and laboratory improvement meals expand, increasing its caloric content and the amount of protein needed for a speedy recovery.Although the set of allowed products is very similar to the already mentioned diet, but the list of dishes on the menu is increased (allowed to bake).If pancreatitis is accompanied by the development of diabetes, the forbidden food list add white porridge, potatoes, honey, sweets and cakes.

Choice medications, their combinations, the duration of their admission should carry a doctor.Self-medication is not permissible, as it can trigger the progression of the disease.After a thorough examination of the particular clinical case your doctor may choose the following medicines.

Analgesics:

Inhibitors of kallikrein protease (pantropin aprotinin, contrycal, tsalol, gordoks et al.), Required in the case of a high level of pancreatic enzymes in the urine and / or serum, as they inhibit progression of the destruction and inflammation of pancreatic tissue.

synthetic hormone somatostatin analogue (Sandostatin, octreotide), reducing the pressure in the ducts of the pancreas and the secretion of pancreatic juice.

Sekretolitiki (medicines that reduce pancreatic secretion):

prokinetics (domperidone, itopride, metoclopramide, trimedat etc.), Regulating the pressure in the ducts of the prostate and eliminate vomiting.

solutions to reduce toxicity (Ringer's acetate, reamberin et al.).

Polifermenty without bile acids (ermital, pancreatin, pankreazim, Creon, mikrazim, pantsitrat et al.).

antidiabetic medications (metformin, Manin, glyurenorm et al.) Or insulin.

Antioxidants (unitiol, thiotriazoline, hypoxia, and others.), Limiting "self-digestion".

immunomodulators (immunofan, thymogen, Pentaglobin et al.).

Physiotherapy restrictions apply after the reduction of inflammatory activity.With intensive pain prescribe electrophoresis with novocaine or dalargin, ultrasound, diadynamic currents.To combat inflammation remaining recommended laser or ultraviolet irradiation of blood, an alternating magnetic field.

often radical treatment is the only way to cope with a serious and severe inflammation, for which does not affect non-surgical techniques.Then it is necessary to resect (completely remove) the affected areas or whole disease of the pancreas.

The attached video file of chronic pancreatitis tells the famous physician and TV presenter Elena Malysheva.

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