August
12
19:53
Cardiology

Alcoholic cardiomyopathy: symptoms, treatment

term "alcoholic cardiomyopathy" is not quite correct.In modern cardiology understood by cardiomyopathy myocardial disease of unknown cause, characterized by an enlarged heart and heart failure progression.Therefore correct to speak about alcohol myocardiodystrophy.This heart disease occurs in people who abuse alcohol, and is characterized by impaired metabolism in the heart muscle cells.

Content

  • 1 mechanism of
  • 2 Clinical forms
  • 3 clinical stage
  • 4 Symptoms
  • 5 Diagnostics
  • 6 Treatment

Alcohol (ethanol) and its decay products - acetaldehyde - have a toxic effect on the cells of the heart muscle.They disrupted energy metabolism, reduces the formation of "fuel" for biological reactions - adenosine triphosphate (ATP).Coma of suffering exchange of calcium, potassium and magnesium, which violates the myocardial contractility.
Ethanol and acetaldehyde cause increased blood concentrations of catecholamines (e.g., norepinephrine), which increases myocardial oxygen demand.Catecholamine

s directly damaging cellular membranes, activate lipid peroxidation, thus contributing to the destruction of heart cells.

description of the clinical forms of alcohol myocardiodystrophy gave in 1977 EM Tara and Mukhin.

stage during alcohol myocardiodystrophy described the VH Vasilenko 1989

Symptoms of alcohol myocardiodystrophy most powerfully manifested in a period of abstinence (within 8 days after an episode of excessive alcohol consumption).

there is swelling in the legs, especially in the evening, and in severe cases - common swelling of the whole body, increasing the abdomen (ascites).Increased liver.

To diagnose alcohol myocardiodystrophy performed electrocardiography, echocardiography (ultrasound of the heart), daily monitoring of an electrocardiogram, exercise test (eg, bicycle ergometry or treadmill test).Required appointed consulting psychiatrist to confirm the diagnosis "alcoholism."

main curative factor - the cessation of alcohol consumption.
To improve the metabolic processes in the myocardium prescribers to stimulate protein synthesis in the cells of the heart (Mildronat), as well as improve energy metabolism (cytochrome C, Neoton etc.).To the same end use multivitamins.
to suppress lipid peroxidation in cellular membranes and damage them termination prescribed antioxidant agents such as vitamin E. When
development of certain types of arrhythmias are assigned calcium antagonists (e.g., verapamil).It affects the metabolism of calcium in cells, providing anti-arrhythmic action.Furthermore, these drugs improve tissue respiration normalized relaxation of myocardial cells, stabilize cell membranes.
to stabilize lysosomal membranes administered Essentiale or Parmidin.As a result, it prevented access to the cells of aggressive lysosomal enzymes and destruction myocardiocytes.
To eliminate oxygen deficiency and "acidification" the internal environment in patients with alcoholic myocardiodystrophy recommended to stay in the fresh air intake of oxygen cocktails, inhalation of humidified oxygen, hyperbaric oxygenation sessions.Furthermore, appointed antihypoxants (eg Mexidol).
To normalize the electrolyte balance of the body is conducted saturation of potassium salts.Appointed potassium diet.It may be recommended intake of potassium chloride together with orange or tomato juice.Often, when you feel unwell preparty potassium intravenously.This is especially important if you have arrhythmias.
To eliminate the effects of excess catecholamines on the myocardium are appointed by beta-blockers (eg, Inderal).With the development of heart failure, arrhythmias, and treatment of these syndromes is performed under the relevant schemes.

more about the kinds of cardiomyopathy and its treatment in the "Live healthy!»:

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